Job Description
Postdoctoral research positions are available in the laboratory of Dr. Fabienne Fiesel to investigate pathogenic mechanisms of neurodegeneration at Mayo Clinic in Jacksonville, Florida.
The Fiesel lab studies molecular pathways that regulate tau biology and protein homeostasis, with a particular interest in UFMylation and how alterations therein contribute to Alzheimer's disease and related neurodegenerative disorders. The lab employs a multi-disciplinary approach using state-of-the-art techniques in cell biology, biochemistry, imaging, and proteomics to illuminate the underlying disease biology in iPSC-derived cell models, in vivo in mice, and in human clinical and neuropathological specimens.
Specific research projects include
1) investigation of mechanisms regulating tau aggregation and propagation in Alzheimer's disease and related tauopathies,
2) identification of UFM1-modified proteins and pathways using biochemical and proteomic approaches,
3) mechanistic studies of tau and UFMylation in iPSC-derived cells and mouse models, as well as
4) genetic and pharmacological modulation of UFMylation as a potential therapeutic strategy.
How to Apply: Qualified candidates should send a cover letter outlining research interests and achievements along with their curriculum vitae to Fabienne Fiesel (Fiesel.Fabienne@mayo.edu).
For an overview of research and laboratory visit: https://www.mayo.edu/research/labs/cellular-mechanisms-neurodegenerativ…
Mayo Clinic and the Department of Neuroscience offer an outstanding research and training environment with a competitive stipend and a generous fringe benefit package.
Qualifications
Applications are invited from highly motivated candidates holding a recent Ph.D. or M.D./Ph.D. with a strong research background in neuroscience, cell biology, or biochemistry. Expertise in iPSC models, mouse work, imaging or proteomics approaches is desirable. In addition, qualified candidates should have a record of impactful, peer-reviewed publications. Excellent verbal and written communication skills in English are essential
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Postdoctoral research positions are available in the laboratory of Dr. Fabienne Fiesel to investigate pathogenic mechanisms of neurodegeneration at Mayo Clinic in Jacksonville, Florida.
The Fiesel lab studies molecular pathways that regulate tau biology and protein homeostasis, with a particular interest in UFMylation and how alterations therein contribute to Alzheimer's disease and related neurodegenerative disorders. The lab employs a multi-disciplinary approach using state-of-the-art techniques in cell biology, biochemistry, imaging, and proteomics to illuminate the underlying disease biology in iPSC-derived cell models, in vivo in mice, and in human clinical and neuropathological specimens.
Specific research projects include
1) investigation of mechanisms regulating tau aggregation and propagation in Alzheimer's disease and related tauopathies,
2) identification of UFM1-modified proteins and pathways using biochemical and proteomic approaches,
3) mechanistic studies of tau and UFMylation in iPSC-derived cells and mouse models, as well as
4) genetic and pharmacological modulation of UFMylation as a potential therapeutic strategy.
How to Apply: Qualified candidates should send a cover letter outlining research interests and achievements along with their curriculum vitae to Fabienne Fiesel (Fiesel.Fabienne@mayo.edu).
For an overview of research and laboratory visit: https://www.mayo.edu/research/labs/cellular-mechanisms-neurodegenerativ…
Mayo Clinic and the Department of Neuroscience offer an outstanding research and training environment with a competitive stipend and a generous fringe benefit package.
Qualifications
Applications are invited from highly motivated candidates holding a recent Ph.D. or M.D./Ph.D. with a strong research background in neuroscience, cell biology, or biochemistry. Expertise in iPSC models, mouse work, imaging or proteomics approaches is desirable. In addition, qualified candidates should have a record of impactful, peer-reviewed publications. Excellent verbal and written communication skills in English are essential
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.